Here's a brand new study that caught my eye. It shows that in subjects with insulin resistance (at the muscle level), there is a lessened response to exercise. In lean subjects, gene expression in the muscles was increased after exercise. In the insulin resistant subjects, there was a lessened response within the particular genes.
Ouch! This almost looks like a case of the fit getting fitter, while the overweight are at a sizable disadvantage. It's much easier to stay in shape than to get in shape...
